Bioreactors and fermenters
Our bioreactors are designed for controlled biological processes involving microorganisms or cell cultures. Each bioreactor or fermenter is configured based on the type of culture, oxygenation requirements, control of critical parameters, and sterility conditions, ensuring biological environment stability throughout the entire process.
Bioreactors and fermenters
Our bioreactors are designed for controlled biological processes involving microorganisms or cell cultures. Each bioreactor or fermenter is configured based on the type of culture, oxygenation requirements, control of critical parameters, and sterility conditions, ensuring biological environment stability throughout the entire process.
Technology and design
Manufacturing volumes between 10 L and 4,000 L
Design pressures from absolute vacuum (-1 barg) to 10 barg
Stainless steel AISI 316L manufacturing
Interior finishes to Ra < 0.4 µm as required
ASME-BPE Configuration for Sterile Applications
Biological cultivation agitation systems
Controlled gassing options: air, O₂, N₂, CO₂
Direct gas inlet or via sparger
Configurable Instrumentation: pH, Dissolved O₂, Temperature, Pressure, Level
Heatable 0.22 µm vent filters
SIP Sterilization Configuration
CIP/SIP System Integration
HMI and SCADA control system
Configurable recipes, 21 CFR compliance, and remote access
Productive versatility
Controlled microbiological fermentation
Designed for processes where microorganisms require a stable environment of temperature, oxygenation, and agitation for their growth and production. They allow for reproducible conditions to be maintained throughout the entire fermentation cycle, ensuring stability and consistency between batches.
Cell culture in a sterile environment
Process-oriented configuration requiring continuous control of pH, dissolved oxygen, and temperature under sterile conditions. The design minimizes contamination risks and facilitates operation in regulated environments.
Biological processes with gas control
The ability to control the intake of air and other gases according to the metabolic needs of the crop. This allows the biological environment to be adapted to each phase of the production process.
Biotechnological batch production
Ready to operate in repeatable cycles with logging and control of critical parameters. They facilitate process standardization.
Media Preparation and Conditioning
Usable for the mixing and thermal control of culture media and biological solutions prior to the main process. They ensure homogeneity and adequate conditions before their transfer to other production stages.
Integration into complete biotech processes
Designed to work alongside dosing, filtration, transfer, and cleaning systems within a biotechnical line.
Key solutions and benefits
Stable environment for biological growth
It keeps the necessary conditions for crop development under control throughout the entire process.
Precise control of crop oxygenation
Allows adjustment of gas supply according to the metabolic needs of the microorganism or cell.
Risk of contamination reduction
Hygienic design and filtration systems help maintain sterile operating conditions.
Sterilize equipment before each cycle
SIP integration allows the reactor to be prepared without interventions or dismantling.
Biotechnological process repeatability
Automation allows maintaining the same operational conditions between batches.
Integration into complete biotech platforms
The equipment connects with media preparation, filtration, or product transfer systems.
Applications
Pharmaceutical sector
Production of recombinant therapeutic proteins
Monoclonal antibody production in phase upstream
Production of bacterial and recombinant vaccines
Production of antibiotics by controlled fermentation
Production of enzymes for pharmaceutical use
Clinical and preclinical batch manufacturing
Culture Media and Buffer Solutions Production
Biological processes in a controlled sterile environment
Biotechnology sector
Viral vector production (AAV, Lentivirus, adenovirus
Biological processes for gene therapy
Cell Expansion for Advanced Therapies
Therapeutic mRNA Production in Biological Phase
Production and conditioning exosomes
Strain Optimization and Bioprocess Development
Strain Optimization and Bioprocess Development
Recombinant protein production
Cosmetics industry
Hyaluronic acid production by fermentation
Recombinant collagen and elastin production
Biological polysaccharide production
Cosmetic Ferments and Biotechnological Extracts
Production of bioactives anti-aging of biological origin
Production of functional peptides dermocosmetics
Development of biotechnological active ingredients
Production of biological compounds for cosmetics
Veterinary sector
Veterinary vaccine production
Antibiotic Production by Fermentation
Veterinary liquid probiotic production
Digestive enzyme production for animal use
Production of fermented biological supplements
Crop and veterinary biomass production
Biological processes for animal formulations
Production of biological compounds for veterinary use